Session 1: Birth of Proteins Focusing on translation mechanisms and the latest research on ribosomes.
Venue: Main Hall (Gold Room)
Judith Frydman - Stanford University
The UFM1 cycle in cellular proteostasis Ron Kopito - Stanford University
Molecular basis and physiological function of the CAT tailing in mammalian RQC. Toshifumi Inada - The University of Tokyo
Precise identification of dark proteins and their functional roles Akinobu Matsumoto - Nagoya University
A presenter from the poster session
15:20–15:40
Coffee Break Venue: Foyer in front of the Main Hall
15:40–17:50
Session 2: Protein Maturation – Chaperones and Folding Focusing on chaperone-mediated protein folding, quality control, and structural formation processes. Venue: Main Hall (Gold Room)
Mechanisms of co-translational folding and assembly of proteins Bernd Bukau - Heidelberg University
Nascent chain tracking to investigate proteostasis events in live cells. Hideki Taguchi - Institute of Science Tokyo
NMR Investigation of Chaperone-Mediated Protein Folding at Residue-Resolution Tomohide Saio - Tokushima University
A presenter from the poster session
Day 2 – August 27 (Wednesday)
10:00–12:05
Session 3: Protein Degradation – Proteasome and Autophagy Focusing on degradation pathways, proteasome function, and autophagy. Venue: Main Hall (Gold Room)
Mechanisms of ER-associated protein degradation Pedro Carvalho - University of Oxford
Mechanism of autophagy initiation by phase separation Yuko Fujioka - Hokkaido University
Autophagy; The Guardian Of Cells Against Diseases And Aging Tamotsu Yoshimori - The University of Osaka
Molecular mechanism of ER stress-dependent co-translational protein degradation Hisae Kadowaki - University of Miyazaki
A presenter from the poster session
12:05–13:30
Lunch (Lunch box provided for all participants)
13:30–15:10
Session 4: Post-translational Modifications and Functional Diversity of Proteins Exploring functional impacts of palmitoylation, phosphorylation, ubiquitination, and other modifications. Venue: Main Hall (Gold Room)
Functional specialisation of the human KDEL Receptors Roberto Sitia - Vita-Salute San Raffaele Universi-ty
Toward Deciphering the Blueprint of Protein Glycosylation: From Molecular Dynamics to the Sub-Golgi Landscape Koichi Kato - National Institutes of Natural Sciences
Toward Finding a Cure for NGLY1 Deficiency Tadashi Suzuki - RIKEN
A presenter from the poster session
15:10–15:30
Coffee Break Venue: Foyer in front of the Main Hall
15:30–17:10
Session 5: Emerging Technologies and the Future of Protein Research New possibilities in protein science enabled by advanced technologies. Venue: Main Hall (Gold Room)
Beyond the Helix: Unprecedented Features of the Filovirus Nucleocapsid Revealed by in situ Cryo-Electron Tomography Reika Watanabe - La Jolla Institute for Immunology
Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq Shintaro Iwasaki - RIKEN
PLOM-CON analysis: Image-based covariation network method to decode dynamic cellular processes Fumi Kano - Institute of Science Tokyo
A presenter from the poster session
17:20–19:00
Poster Session
Odd-numbered posters : 17:20–18:10
Even-numbered posters: 18:10–19:00
Venue: Royal Room
Day 3 – August 28 (Thursday)
09:00–10:50
Session 6: Stress Responses and Cellular Adaptation Discussing ISR, UPR, and physiological/pathological roles of protein aggregation. Venue: Main Hall (Gold Room)
DNAJB6: guardian of protein phase transitions and facilitator of aggregate disposal Harm H. Kampinga - University Medical Center Groningen
Dynamic Regulation of the Proteasome by ECPS-1/Ecm29 Nicolas Lehrbach - Fred Hutchinson Cancer Center
A Motor Neuron Disease-associated Mutation Produces Non-glycosylated Seipin that Induces ER Stress and Apoptosis by Inactivating SERCA2b Kazutoshi Mori - Kyoto University
A presenter from the poster session
10:50–11:10
Coffee Break Venue: Foyer in front of the Main Hall
11:10–13:15
Session 7: Organellostasis – Maintaining Intracellular Homeostasis Exploring inter-organelle coordination and roles of protein transport. Venue: Main Hall (Gold Room)
The identification of rare genetic variants linked to protein conformational disease and quality control Jeffrey L. Brodsky - University of Pittsburgh
Autophagy-Mediated Quality Control and Functional Recovery in the Nervous System Noboru Mizushima - The University of Tokyo
Crosstalk between metallostasis and proteostasis at the ER-Golgi interface Kenji Inaba - Kyushu University
"ERAD body" as a novel platform for endoplasmic reticulum protein quality control Ryo Ushioda - Kyoto Sangyo University
A presenter from the poster session
13:15–17:30
Lunch & Excursion (Optional)
17:30–18:30
Session 8: Special Lecture
Venue: Main Hall
Heat Shock to Proteostasis Richard I. Morimoto - Northwestern University
18:30–
Reception Venue: Royal Room
Day 4 – August 29 (Friday)
10:00–11:40
Session 9: Pathogenic Protein Aggregation and Related Diseases Insights into diseases caused by aggregation-prone proteins, including amyloidosis and neurodegenerative disorders. Venue: Main Hall (Gold Room)
Ronald Melki - University Paris-Saclay
Deciphering prion strains by in vitro-generated amyloid fibrils Motomasa Tanaka - RIKEN
Molecular mechanisms of Neurodegeneration induced by RNA G-quadruplexes Yasushi Yabuki - Kumamoto University